Volume 5, Issue 12 p. 3503-3507
Full Paper

Efficient and Uncatalyzed Synthesis of Highly Functionalized New Symmetrical Indeno[1,2-b]pyrroles via a One-Pot Four-Component Reaction

Dr. Atieh Rezvanian

Corresponding Author

Dr. Atieh Rezvanian

Department of Chemistry, School of Science, Alzahra University, POBox, 1993891176 Vanak, Tehran, Iran

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Fahame Mahmoodi

Fahame Mahmoodi

Department of Chemistry, School of Science, Alzahra University, POBox, 1993891176 Vanak, Tehran, Iran

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Dr. Vahideh Zadsirjan

Dr. Vahideh Zadsirjan

Department of Chemistry, School of Science, Alzahra University, POBox, 1993891176 Vanak, Tehran, Iran

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Mehri Salimi

Mehri Salimi

Department of Chemistry, School of Science, Alzahra University, POBox, 1993891176 Vanak, Tehran, Iran

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Prof. Majid M. Heravi

Corresponding Author

Prof. Majid M. Heravi

Department of Chemistry, School of Science, Alzahra University, POBox, 1993891176 Vanak, Tehran, Iran

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First published: 24 March 2020
Citations: 4

Graphical Abstract

A facile, efficient and un-catalyzed approach for the synthesis of new symmetrical highly- substituted indeno [1,2-b]pyrrole derivatives through four-component reaction, involving, primary amines, diamine, diketene, and ninhydrin in CH2Cl2 at ambient temperature is reported. This approach enjoys merits such as being done in the absence of catalyst at ambient temperature, giving good to excellent yields, completed in short reaction times, and showing a wide functional group tolerance.

Abstract

A facile, efficient and un-catalyzed approach for the synthesis of new symmetrical highly- substituted indeno [1,2-b]pyrrole derivatives through four-component reaction, involving, primary amines, diamine, diketene, and ninhydrin in CH2Cl2 at ambient temperature is reported. This approach enjoys merits such as being done in the absence of catalyst at ambient temperature, giving good to excellent yields, completed in short reaction times, and showing a wide functional group tolerance.

Conflict of interest

The authors declare no conflict of interest.